How can a single hospital outbreak illustrate the mechanisms of antibiotic resistance spread?

Question

A student studying infectious disease wants to understand how antibiotic resistance can spread within a hospital setting. What are the key factors and steps in a real-world outbreak that demonstrate this process?

Answer

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A 2015 ICU outbreak of carbapenem-resistant Klebsiella showed how selective pressure, clonal spread, and lapses in hygiene can fuel resistance within hospitals....

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